Citalopram Impurity 16 CAS 762266-07-9
| CAS No. | 762266-07-9 |
| Molecular Formula | C21H15F2NO2 |
| Molecular Weight | 351.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Citalopram Impurity 16 (CAS 762266-07-9), a pharmacopoeial impurity reference standard (molecular formula C21H15F2NO2, MW 351.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Citalopram Impurity 16 (C21H15F2NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 351.35 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Citalopram Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H15F2NO2 |
| Molecular Weight | 351.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Citalopram Standards
- Citalopram Impurity 76 (CAS CATO-C4X-110976)
- Citalopram-d6 N-Oxide (CAS 1189652-54-7)
- (R)-Citalopram-d6 N-Oxide (CAS 1217669-62-9)
- (S)-Citalopram-d6 N-Oxide (CAS 1217710-65-0)
- Citalopram Impurity 75 (CAS CATO-C4X-110975)
- Citalopram impurity 79 (CAS CATO-C4X-110979)
- Citalopram Impurity 65 (CAS CATO-C4X-110965)
- Citalopram EP Impurity M (CAS 440121-09-5)
Recommended Standards
- 1-amino-1,10-dioxo-5,8,14,17-tetraoxa-2,11-diazanonadecan-19-oic acid (CAS CATO-C3D-262302)
- Lansoprazole impurity 72 (CAS 2138848-89-0)
- N-(4-((2-cyano-5-(trifluoromethyl)pyridin-3-yl)thio)phenyl)propionamide (CAS 338420-06-7)
- Nintedanib Impurity 13 (CAS 1253769-13-9)
- Tacrolimus EP Impurity C (CAS CATO-C4X-130025)
- Diquafosol Impurity 28 (CAS CATO-C4X-214928)
- Baloxavir Marboxil Impurity 175 (CAS CATO-C4X-2108175)
- 2-(5-Methyl-1h-1,2,3,4-tetrazol-1-yl)ethan-1-amine dihydrochloride (CAS 1311318-17-8)
- 3-[(tert-Butyldimethylsilyl)oxy]-4-fluorophenol (CAS 1881329-11-8)
- 2,4,6-Trimethoxyquinoline-3-carbaldehyde (CAS 51179-19-2)
- 4-Methyl-2-(4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(phenylcarbamothioyl)pentanamide (CAS 72045-76-2)
- Benzyl 2,4-dioxo-3,4,5,6,8,9-hexahydro-1H-pyrimido[4,5-d]azepine-7(2H)-carboxylate (CAS 1207369-43-4)
- tert-Butyl 2-(4-chloro-2-methoxyphenoxy)acetate (CAS 937817-42-0)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com