5-Nitro-2-(1H-pyrazol-1-yl)pyridine CAS 76228-53-0
| CAS No. | 76228-53-0 |
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 190.16 g/mol gives 5-Nitro-2-(1H-pyrazol-1-yl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Nitro-2-(1H-pyrazol-1-yl)pyridine (CAS 76228-53-0) is a high-purity analytical reference standard with the molecular formula C8H6N4O2 and a molecular weight of 190.16 g/mol.
The molecular framework of 5-Nitro-2-(1H-pyrazol-1-yl)pyridine (C8H6N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Nitro-2-(1H-pyrazol-1-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6N4O2 |
| Molecular Weight | 190.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 4 |
Related Nitro Standards
- 6-Nitro-1H-indole-3-carbaldehyde (CAS 10553-13-6)
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Recommended Standards
- 5-Nitro-1H-quinolin-2-one (CAS 6938-27-8)
- 5-Nitroisoquinolin-1(2H)-one (CAS 82827-08-5)
- 5-Nitro-1H-indole-3-carbaldehyde (CAS 6625-96-3)
- 5-Nitroisoquinolin-3-ol (CAS 581813-27-6)
- Ethyl furo[3,2-b]pyridine-5-carboxylate (CAS 182691-69-6)
- (24aS)-5,6,8,9,11,12,14,15,17,18 ,23,24,25,26-tetradecahydro-diindeno[7,1-qr:1',7'-st][1,4,7,10,13,16]hexaoxacycloheneicosin (CAS 881176-31-4)
- 5-Bromo-1H-benzo[d][1,3]oxazin-2(4H)-one (CAS 861106-93-6)
- 3-(4-Chlorophenyl)pyridine-2-carbonitrile (CAS 1355247-94-7)
- 5-(3-Methylthiophen-2-yl)isoxazole-3-carboxylic acid (CAS 668971-22-0)
- 3,3,5-Trimethylindolin-7-ol (CAS 222721-48-4)
- Hg in water quality (CAS CATO-CQCM102198)
- 2-(Pyridin-3-yl)-6-(trifluoromethyl)nicotinic acid (CAS 1214335-49-5)
- 2-(Phenoxymethyl)tetrahydrofuran (CAS 46235-50-1)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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