3-amino-2,2-difluoro-3-phenylpropanamide CAS 762293-09-4
| CAS No. | 762293-09-4 |
| Molecular Formula | C9H10F2N2O |
| Molecular Weight | 200.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-amino-2,2-difluoro-3-phenylpropanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-amino-2,2-difluoro-3-phenylpropanamide (CAS 762293-09-4), a certified reference material (molecular formula C9H10F2N2O, MW 200.19 g/mol) for analytical method development and quality control.
The molecular framework of 3-amino-2,2-difluoro-3-phenylpropanamide (C9H10F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H10F2N2O |
| Molecular Weight | 200.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-Amino-3-methyl-N-((R)-1-phenylethyl)pentanamide (CAS 1354204-43-5)
- 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one hydrochloride (CAS 76536-65-7)
- Tepotinib Impurity 35 (CAS 1103507-32-9)
- N-(3-bromophenyl)-1,2,3,4-thiatriazol-5-amine (CAS 1904016-66-5)
- 2-((1-Methyl-1h-tetrazol-5-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 271798-73-3)
- (4-Bromo-2,5-difluorophenyl)(cyclopropyl)methanone (CAS 1343347-87-4)
- N-(Oxan-4-yl)acetamide (CAS 854696-51-8)
- N-[(3-Chloro-4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carboxamide (CAS 866132-01-6)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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