3-Chloro-4-propoxybenzoyl chloride CAS 76327-33-8

Purity 97%+In StockPharmaceutical Standards
CAS No.76327-33-8
Molecular FormulaC10H10Cl2O2
Molecular Weight233.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-4-propoxybenzoyl chloride CAS 76327-33-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-4-propoxybenzoyl chloride.

CATO supplies 3-Chloro-4-propoxybenzoyl chloride (CAS 76327-33-8), a certified reference material (molecular formula C10H10Cl2O2, MW 233.09 g/mol) for analytical method development and quality control.

The molecular framework of 3-Chloro-4-propoxybenzoyl chloride (C10H10Cl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Chloro-4-propoxybenzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10Cl2O2
Molecular Weight233.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978
Halogen ContentCl-containing

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