Ethyl 5-(4-chlorophenyl)isoxazole-4-carboxylate CAS 76344-83-7
| CAS No. | 76344-83-7 |
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-(4-chlorophenyl)isoxazole-4-carboxylate.
CATO supplies Ethyl 5-(4-chlorophenyl)isoxazole-4-carboxylate (CAS 76344-83-7), a certified reference material (molecular formula C12H10ClNO3, MW 251.67 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 5-(4-chlorophenyl)isoxazole-4-carboxylate (C12H10ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 5-(4-chlorophenyl)isoxazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO3 |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(2-(2-Chlorophenyl)-5-methyloxazol-4-yl)acetic acid (CAS 1017181-48-4)
- 2-(2-(3-Chlorophenyl)-5-methyloxazol-4-yl)acetic acid (CAS 1017231-31-0)
- 1-(3-Chlorophenyl)-5-ethyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1017457-41-8)
- 2-[1-(3-chlorophenyl)-5-methyl-1h-1,2,3-triazol-4-yl]acetic acid (CAS 1017457-61-2)
- 1-(2-Chlorophenyl)-5-ethyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017458-30-8)
- 6-((2-Chlorophenyl)amino)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 112069-51-9)
- Ethyl 5-(2-Chlorophenyl)isoxazole-3-carboxylate (CAS 1126636-57-4)
- Methyl 1-(4-Chlorophenyl)-5-methyl-1,2,3-triazole-4-carboxylate (CAS 1147199-25-4)
Recommended Standards
- Ethyl 5-(4-chlorophenyl)-1h-1,2,4-triazole-3-carboxylate (CAS 62230-51-7)
- Ethyl 5-(4-chlorophenyl)oxazole-2-carboxylate (CAS 2082-14-6)
- Ethyl 5-(3-chlorophenyl)oxazole-2-carboxylate (CAS 400715-69-7)
- Ethyl 5-chloro-1-(pyridin-2-yl)-1H-pyrazole-4-carboxylate (CAS 98475-61-7)
- n-(1-(P-tolyl)ethyl)propan-2-amine (CAS 1021076-96-9)
- 2-{[5-(furan-2-yl)-4-(2-methylprop-2-en-1-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 307327-49-7)
- 2-(Chloromethyl)-6-cyano-5-(difluoromethyl)-3-nitropyridine (CAS 1805973-39-0)
- Benzenemethanol, 4-(4,5-dihydro-4-phenyl-2-oxazolyl)-, (R)- (CAS 174770-64-0)
- Benzyl 1,8-diazaspiro[5.5]Undecane-8-carboxylate hydrochloride (CAS 1439896-71-5)
- 1142215-80-2 9470AC C20H24N2O6 [{2-[(3,4-Dimethoxybenzyl)amino]-2-oxoethyl}-(4-methoxyphenyl)amino]acetic acid (CAS 1142215-80-2)
- Ethylcarbamic Acid 1-(Phenylmethyl)-4-piperidinyl Ester (CAS 71879-62-4)
- Methyl 4-oxo-3-propyl-3,4-dihydrophthalazine-1-carboxylate (CAS 565173-11-7)
- N-(4-Acetylphenyl)-2-bromoacetamide (CAS 29182-93-2)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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