2-(Methylthio)-N-(4-(trifluoromethoxy)phenyl)nicotinamide CAS 764705-17-1

Purity 97%+In StockPharmaceutical Standards
CAS No.764705-17-1
Molecular FormulaC14H11F3N2O2S
Molecular Weight328.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Methylthio)-N-(4-(trifluoromethoxy)phenyl)nicotinamide CAS 764705-17-1 chemical structure

Description

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(Methylthio)-N-(4-(trifluoromethoxy)phenyl)nicotinamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies 2-(Methylthio)-N-(4-(trifluoromethoxy)phenyl)nicotinamide (CAS 764705-17-1), a certified reference material (molecular formula C14H11F3N2O2S, MW 328.31 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Methylthio)-N-(4-(trifluoromethoxy)phenyl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H11F3N2O2S
Molecular Weight328.31 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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