(2-Chloromethoxyethyl)trimethylsilane 2-(Trimethylsilyl)ethoxymethyl chloride 76513-69-4 Chloromethyl 2-trimethylsilylethyl ether SEM-Cl SEM-chloride CAS 76513-69-4

Purity 97%+In StockPharmaceutical Standards
CAS No.76513-69-4
Molecular FormulaC6H15ClOSi
Molecular Weight166.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Chloromethoxyethyl)trimethylsilane 2-(Trimethylsilyl)ethoxymethyl chloride 76513-69-4 Chloromethyl 2-trimethylsilylethyl ether SEM-Cl SEM-chloride CAS 76513-69-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(2-Chloromethoxyethyl)trimethylsilane 2-(Trimethylsilyl)ethoxymethyl chloride 76513-69-4 Chloromethyl 2-trimethylsilylethyl ether SEM-Cl SEM-chloride (CAS 76513-69-4) is a high-purity analytical reference standard with the molecular formula C6H15ClOSi and a molecular weight of 166.72 g/mol.

Owing to a hydroxyl group, an ether linkage, chlorine substitution, (2-Chloromethoxyethyl)trimethylsilane 2-(Trimethylsilyl)ethoxymethyl chloride 76513-69-4 Chloromethyl 2-trimethylsilylethyl ether SEM-Cl SEM-chloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 166.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H15ClOSi
Molecular Weight166.72 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)-1.0
CAS Registry Year (est.)1978
Halogen ContentCl-containing

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