(R)-3-(4-chlorophenyl)pyrrolidine CAS 765247-87-8
| CAS No. | 765247-87-8 |
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, (R)-3-(4-chlorophenyl)pyrrolidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(R)-3-(4-chlorophenyl)pyrrolidine (CAS 765247-87-8) is a high-purity analytical reference standard with the molecular formula C10H12ClN and a molecular weight of 181.66 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-3-(4-chlorophenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (R)-2-(2-Chlorophenyl)pyrrolidine (CAS 823188-58-5)
- (S)-1-(2-chlorophenyl)but-3-en-1-amine (CAS 224453-37-6)
- (R)-1-(4-chlorophenyl)but-3-en-1-amine (CAS 698378-82-4)
- (S)-1-(4-chlorophenyl)but-3-en-1-amine (CAS 245735-57-3)
- 1100273-14-0 4-(Nitrooxy)butyl butanoate 8687AC C8H15NO5 (CAS 1100273-14-0)
- 5-(6-Chloropyridazin-3-yl)-4-methyl-2-phenylthiazole (CAS 1105195-31-0)
- 7-Chloro-1-isopropylimidazo[1,5-c]pyrimidine-3-carbaldehyde (CAS 1956382-08-3)
- 2-(4-Isocyanophenyl)acetonitrile (CAS 216063-67-1)
- N-[(1R*,4R*)-4-Aminocyclohexyl]-2-methoxyacetamide hydrochloride (CAS 1286275-78-2)
- 2-(Trifluoromethyl)benzo[d]thiazol-6-amine (CAS 58460-20-1)
- (3-Bromo-4-iodophenyl)methanamine (CAS 1261553-01-8)
- 3-(Aminomethyl)-3-methylpentan-2-ol (CAS 1423025-94-8)
- 4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1708269-58-2)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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