2-Bromo-5-isocyanatothiophene CAS 76537-03-6
| CAS No. | 76537-03-6 |
| Molecular Formula | C5H2BrNOS |
| Molecular Weight | 204.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-5-isocyanatothiophene is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-5-isocyanatothiophene (CAS 76537-03-6) is a high-purity analytical reference standard with the molecular formula C5H2BrNOS and a molecular weight of 204.04 g/mol.
The molecular framework of 2-Bromo-5-isocyanatothiophene (C5H2BrNOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Bromo-5-isocyanatothiophene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2BrNOS |
| Molecular Weight | 204.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 2-Bromo-5-fluorobenzylamine (CAS 747392-34-3)
- 3-Bromo-2-fluoro-5,6-dimethylpyridine (CAS 2137579-23-6)
- 2-Bromo-5-fluoro-4-methylaniline (CAS 202865-78-9)
- 3-bromo-2-isocyanatothiophene (CAS 76537-10-5)
- 5-Bromo-1-methyl-1H-pyrazin-2-one (CAS 1243288-53-0)
- 1158247-58-5 2-Amino-6-(4-aminopiperidin-1-yl)pyrimidin-4(1H)-one--hydrogen chloride (1/2) DTXSID20700651 (CAS 1158247-58-5)
- (6-ethoxy-3-pyridyl)hydrazine (CAS 1935267-58-5)
- 1-(Cyclohexylamino)-3-((2-methyl-1H-indol-4-yl)oxy)propan-2-ol (CAS 338392-09-9)
- (2-(1H-pyrazol-1-yl)pyridin-4-yl)boronic acid (CAS 1644060-50-3)
- N-(Furan-2-ylmethyl)imidazo[1,2-a]pyrimidin-5-amine (CAS 88443-53-2)
- 4-Amino-5-(4-bromobenzoyl)-N-methylisoxazole-3-carboxamide (CAS 830326-85-7)
- Chloride Ionophore IV (CAS 187404-67-7)
- N-((Isopropoxycarbonyl)oxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-67-2)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
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