1-Phenylpropane-2-sulfonyl chloride CAS 76653-18-4
| CAS No. | 76653-18-4 |
| Molecular Formula | C9H11ClO2S |
| Molecular Weight | 218.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Phenylpropane-2-sulfonyl chloride.
CATO supplies 1-Phenylpropane-2-sulfonyl chloride (CAS 76653-18-4), a certified reference material (molecular formula C9H11ClO2S, MW 218.70 g/mol) for analytical method development and quality control.
The molecular framework of 1-Phenylpropane-2-sulfonyl chloride (C9H11ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Phenylpropane-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO2S |
| Molecular Weight | 218.70 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Phenylpropane Standards
- 2-Phenylpropane-1-sulfonyl chloride (CAS 102879-16-3)
- 2-Methyl-1-phenylpropane-1-sulfonamide (CAS 1249032-33-4)
- 2-Methyl-2-phenylpropane-1-sulfonyl chloride (CAS 125125-33-9)
- 1-phenylpropane-1-sulfonamide (CAS 1247494-45-6)
- 2-Phenylpropane-1-sulfonamide (CAS 76653-16-2)
- 3-Phenylpropane-1-sulfonamide (CAS 90220-25-0)
- 3-phenylpropane-1-thiol (CAS 24734-68-7)
- 2-Methyl-1-phenylpropane-1-thiol (CAS 113682-52-3)
Recommended Standards
- 1-Chloronaphtho[2,1-b]thiophene (CAS 85992-26-3)
- 2-(4-Methylphenyl)ethane-1-sulfonyl chloride (CAS 88106-95-0)
- 1-Chloro-4-(isopropylsulfonyl)benzene (CAS 7205-83-6)
- 2-(M-tolyl)ethane-1-sulfonyl chloride (CAS 728919-63-9)
- 3-(3,4-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 36685-66-2)
- 3-(6-Hydroxy-7-methoxybenzofuran-5-yl)propanoic acid (CAS 102826-90-4)
- N-(2-(7-Methoxy-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)pentanamide (CAS 851405-44-2)
- 6-Bromo-2-fluoronicotinaldehyde (CAS 1227588-87-5)
- 2-Bromo-7,7-dimethyl-5,6,7,8-tetrahydro-4H-thiazolo[5,4-c]azepin-4-one (CAS 913718-58-8)
- (5-Amino-2-chlorophenyl)(azepan-1-yl)methanone (CAS 926250-53-5)
- 2-Hydroxy-5,7-dimethyl-2,3-dihydro-1H-pyrazolo[1,2-a]pyrazol-4-ium chloride (CAS 1078584-72-1)
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- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
Why CATO?
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