4-Ethoxy-3,5-diiodopyridine CAS 767333-76-6
| CAS No. | 767333-76-6 |
| Molecular Formula | C7H7I2NO |
| Molecular Weight | 374.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Ethoxy-3,5-diiodopyridine (CAS 767333-76-6) is a high-purity analytical reference standard with the molecular formula C7H7I2NO and a molecular weight of 374.95 g/mol.
The molecular framework of 4-Ethoxy-3,5-diiodopyridine (C7H7I2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Ethoxy-3,5-diiodopyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7I2NO |
| Molecular Weight | 374.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Ethoxy Standards
- 2-(2-Ethoxy-4-formylphenoxy)-N,N-diphenylacetamide (CAS 247592-96-7)
- [2-(4-Ethoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-acetic acid (CAS 554439-43-9)
- 4-Ethoxy-2-(piperazin-1-yl)-7-(pyridin-4-yl)-5H-pyrimido[5,4-b]indole (CAS 1034194-07-4)
- 4-Ethoxy-6-methoxy-2-methyl-1-tosyl-1,2-dihydroquinoline (CAS 34129-49-2)
- 2-(3-Ethoxy-4-propoxybenzylidene)-6-methyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 617694-39-0)
- N-(6-Ethoxy-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclohexanecarboxamide (CAS 865174-30-7)
- 4-Ethoxy-3-(3-(4-fluorophenyl)ureido)benzene-1-sulfonyl chloride (CAS 678186-02-2)
- 2-[(6-Ethoxy-2-benzothiazolyl)thio]-N-phenethylacetamide (CAS 5348-88-9)
Recommended Standards
- 3,5-Diiodo-4-methoxyaniline (CAS 496801-28-6)
- Ethyl 2-(chloromethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-thieno[2,3-d]imidazole-5-carboxylate (CAS 2749608-79-3)
- 2-((4-Chlorobenzyl)thio)-3-(thiophen-2-yl)-1,4-diazaspiro[4.5]deca-1,3-diene (CAS 1276469-63-6)
- Methyl (3,5-dibromo-4-(difluoromethoxy)phenyl)carbamate (CAS 84970-91-2)
- N-(4-(((5-Nitrofuran-2-yl)methyl)thio)phenyl)acetamide (CAS 61266-73-7)
- 2,7-Dichloroquinoline-3-carbonitrile (CAS 158583-91-6)
- Fmoc-2,3-difluoro-L-homophenylalanine (CAS 1260609-44-6)
- n-[(3-hydroxyphenyl)methyl]pyridine-4-carboxamide (CAS 1178687-11-0)
- (S)-tert-Butyl 3-aminobutanoate (CAS 161105-54-0)
- 6-(piperazin-1-yl)pyridine-3-carboxylic acid hydrochloride (CAS 1955493-81-8)
- 3-(Dimorpholinophosphoryl)benzo[d]oxazol-2(3H)-one (CAS 59349-95-0)
- 2-(Dimethylamino)-6,7-dimethoxy-4H-3,1-benzoxazin-4-one (CAS 865660-66-8)
- 4-(Dimethylamino)-2-[(3-methylphenyl)sulfanyl]pyridine-3-carbonitrile (CAS 478262-63-4)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com