Bis(trimethylsilyl) but-2-ynedioate CAS 76734-92-4

Purity 97%+In StockPharmaceutical Standards
CAS No.76734-92-4
Molecular FormulaC10H18O4Si2
Molecular Weight258.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Bis(trimethylsilyl) but-2-ynedioate CAS 76734-92-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 258.42 g/mol gives Bis(trimethylsilyl) but-2-ynedioate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Bis(trimethylsilyl) but-2-ynedioate (CAS 76734-92-4), a certified reference material (molecular formula C10H18O4Si2, MW 258.42 g/mol) for analytical method development and quality control.

The molecular framework of Bis(trimethylsilyl) but-2-ynedioate (C10H18O4Si2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H18O4Si2
Molecular Weight258.42 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1978

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