1-(2,2-difluoroethyl)piperazine CAS 767609-14-3
| CAS No. | 767609-14-3 |
| Molecular Formula | C6H12F2N2 |
| Molecular Weight | 150.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,2-difluoroethyl)piperazine (CAS 767609-14-3), molecular formula C6H12F2N2 and molecular weight 150.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,2-difluoroethyl)piperazine (C6H12F2N2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2,2-difluoroethyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H12F2N2 |
| Molecular Weight | 150.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 1-(4-(3-Fluoropropoxy)benzyl)piperidine (CAS 860648-59-5)
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- N-methyl-4-oxo-1-(p-tolyl)-1,4-dihydropyridazine-3-carboxamide (CAS 478063-55-7)
- 5-Ethoxy-N-methyl-4,5-dihydroisoxazole-3-carboxamide (CAS 144537-11-1)
- 5-Chlorothiabendazole (CAS 142383-75-3)
- 8-Fluoro-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1537310-76-1)
- 4-Methyl-6-(pentylsulfonyl)quinolin-2(1H)-one (CAS 1207858-41-0)
- Ethyl 7-[2-(azetidinomethyl)phenyl]-7-oxoheptanoate (CAS 898755-61-8)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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