N-Butyl-2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine CAS 76781-36-7
| CAS No. | 76781-36-7 |
| Molecular Formula | C16H27N5 |
| Molecular Weight | 289.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-Butyl-2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine (CAS 76781-36-7) is a high-purity analytical reference standard with the molecular formula C16H27N5 and a molecular weight of 289.42 g/mol.
Structurally, N-Butyl-2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine (C16H27N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 289.42 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H27N5 |
| Molecular Weight | 289.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 5 |
Recommended Standards
- N,N-Diethyl-2-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine (CAS 76781-40-3)
- 2-Bromo-4-chloro-3,5,6-trifluorobenzoic acid (CAS 1893096-74-6)
- 4-Methoxy-2-{9-methyl-3,9-diazaspiro[5.5]undecan-3-yl}aniline (CAS 2173083-57-1)
- 3-O-Methyl Estradiol-d3 (CAS 57983-88-7)
- 1-(6-(Dimethylamino)naphthalen-2-yl)prop-2-en-1-one (CAS 86636-92-2)
- 2-(2,3,4,5,6-pentadeuteriophenyl)acetonitrile 70026-36-7 (CAS 70026-36-7)
- 4,4,7-Triethoxy-7-methyl-3,8-dioxa-4,7-disiladecane (CAS 18418-54-7)
- Dimethyloxirane-2-carbonitrile (CAS 6509-07-5)
- N-(2-Methoxyphenyl)-4-phenylpiperazine-1-carboxamide (CAS 881987-96-8)
- (4-Chlorophenyl)(3,4-dimethoxyphenyl)methanol (CAS 844683-39-2)
- 1-(4-Chlorophenoxy)cyclohexane-1-carboxylic acid (CAS 17413-88-6)
- 2-(Benzo[d][1,3]dioxol-5-yl)-2-chloroacetamide (CAS 873380-46-2)
- (R)-1-(tert-Butoxycarbonyl)-4-methylpiperazine-2-carboxylic acid (CAS 363192-62-5)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
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