(R)-2-(4-Chlorophenyl)piperazine CAS 769944-51-6
| CAS No. | 769944-51-6 |
| Molecular Formula | C10H13ClN2 |
| Molecular Weight | 196.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-2-(4-Chlorophenyl)piperazine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(R)-2-(4-Chlorophenyl)piperazine (CAS 769944-51-6) is a high-purity analytical reference standard with the molecular formula C10H13ClN2 and a molecular weight of 196.68 g/mol.
(R)-2-(4-Chlorophenyl)piperazine (C10H13ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-2-(4-Chlorophenyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13ClN2 |
| Molecular Weight | 196.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related R Standards
- 1-(2-chlorophenyl)pyrrolidin-3-amine (CAS 1178297-20-5)
- 1-(3-Chlorophenyl)pyrrolidin-3-amine (CAS 1178748-87-2)
- 1-(4-Chlorophenyl)pyrrolidin-3-amine (CAS 1181375-65-4)
- (S)-2-(2-Chlorophenyl)piperazine (CAS 1213129-55-5)
- (S)-2-(4-Chlorophenyl)piperazine (CAS 1213164-34-1)
- n-(3-Chlorophenyl)pyrrolidin-3-amine (CAS 1378522-48-5)
- 3-(4-Chlorophenyl)-5-methyl-1H-pyrazole (CAS 17629-27-5)
- 1-(4-Chlorophenyl)piperazine (CAS 38212-33-8)
Recommended Standards
- 2-Chloro-5-(1-methyl-2-pyrrolidinyl)pyridine (CAS 185510-30-9)
- (S)-2-Chloro-3-(1-methylpyrrolidin-2-yl)pyridine (CAS 40316-89-0)
- 2-Chloro-4-isopropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1824460-59-4)
- 1-((6-Chloropyridin-2-yl)methyl)cyclobutan-1-amine (CAS 2358095-38-0)
- 1-Chloro-2-naphthoic acid (CAS 13029-23-7)
- Chloro[tri(o-tolyl)phosphine]gold(I) (CAS 83076-07-7)
- (R)-1-(6-Chloropyridin-3-yl)ethanamine (CAS 1213062-83-9)
- 2-Bromo-4-methylpyrimidin-5-amine (CAS 1251032-89-9)
- 4-Chloro-2-methyl-6-(methylsulfanyl)pyrimidine (CAS 867131-59-7)
- 8-Chloro-1-octene (CAS 871-90-9)
- 3-((1-Cyclopropyl-1h-tetrazol-5-yl)thio)propan-1-ol (CAS 1153278-96-6)
- Methyl (2S,4S)-4-(trifluoromethyl)pyrrolidine-2-carboxylate (CAS 1860943-65-2)
- 2-(Difluoromethyl)-5-iodo-3-nitropyridine-6-carboxaldehyde (CAS 1806862-92-9)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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