1-(3-Fluorophenyl)-N,N-dimethylmethanamine CAS 770-18-3
| CAS No. | 770-18-3 |
| Molecular Formula | C12H8N2O4 |
| Molecular Weight | 244.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Fluorophenyl)-N,N-dimethylmethanamine (CAS 770-18-3) is a high-purity analytical reference standard with the molecular formula C12H8N2O4 and a molecular weight of 244.20 g/mol.
1-(3-Fluorophenyl)-N,N-dimethylmethanamine (C12H8N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8N2O4 |
| Molecular Weight | 244.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)-1-methyl-4-(trifluoromethyl)-1H-imidazole (CAS 33469-33-9)
- 1-(4-Fluorophenyl)-6-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1094377-62-4)
- 1-(4-Fluorophenyl)-4-methyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one (CAS 1105196-48-2)
- 1-[(2-Fluorophenyl)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1207022-53-4)
- (E)-1-(4-Fluorophenyl)-2-(hydroxyimino)-2-(pyridin-4-yl)ethanone (CAS 152121-33-0)
- 6-(4-Fluorophenyl)-1,3-benzodioxole-5-carbaldehyde (CAS 927802-53-7)
- Methyl 5-((2-fluorophenyl)ethynyl)-furan-2-carboxylate (CAS 725228-58-0)
- 1-(2-Fluorophenyl)-4-hydrazinyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1310122-61-2)
Recommended Standards
- 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 4348-61-2)
- 1-(3-Oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 866144-60-7)
- [4,4'-Bipyridine]-3,3'-dicarboxylic acid (CAS 23245-77-4)
- 1,3,6-Trihydroxy-9H-xanthen-9-one (CAS 39731-47-0)
- 1-Methyl-3-[[5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridyl]amino]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-one (CAS 1433849-83-2)
- N-(2-chlorophenyl)-1-(2,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 338407-95-7)
- 4-Methyl-2-(p-tolylethynyl)aniline (CAS 1258510-98-3)
- 2-(4-Chlorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine (CAS 89569-59-5)
- 3-methyl-1-(pyrrolidin-1-ylcarbonyl)-1H-imidazol-3-ium iodide (CAS 433302-49-9)
- (S)-1-(4-fluoro-3-(trifluoromethyl)phenyl)-2-methylpropan-1-amine (CAS 1213333-46-0)
- 3-(Trifluoromethoxy)pyrazine-2-carboxylic acid (CAS 1261476-61-2)
- Dimethylserine (CAS 2812-35-3)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)butan-1-one (CAS 24283-71-4)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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