(S)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid CAS 770673-87-5

Purity 97%+In StockPharmaceutical Standards
CAS No.770673-87-5
Molecular FormulaC10H9ClF3NO2
Molecular Weight267.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(S)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid CAS 770673-87-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(S)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid (CAS 770673-87-5), molecular formula C10H9ClF3NO2 and molecular weight 267.63 g/mol, is a CATO reference standard with documented purity and traceability.

(S)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid (C10H9ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), (S)-2-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H9ClF3NO2
Molecular Weight267.63 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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