3-Amino-4,4-difluorobutanoic acid CAS 77162-46-0
| CAS No. | 77162-46-0 |
| Molecular Formula | C4H7F2NO2 |
| Molecular Weight | 139.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Amino-4,4-difluorobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Amino-4,4-difluorobutanoic acid (CAS 77162-46-0), molecular formula C4H7F2NO2 and molecular weight 139.10 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-4,4-difluorobutanoic acid (C4H7F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C4H7F2NO2 |
| Molecular Weight | 139.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-Amino-4,4-difluorobutanoic acid (CAS 107910-31-6)
- (S)-2-Amino-4,4-difluorobutanoic acid (CAS 121960-22-3)
- 4-Amino-3,3-difluorobutanoic acid (CAS 1258651-00-1)
- 4-Amino-2,2-difluorobutanoic acid (CAS 130592-02-8)
- (R)-2-Amino-4,4-difluorobutanoic acid (CAS 185348-78-1)
- 2-Amino-3,3-difluoro-2-methyl-propionic acid (CAS 67654-65-3)
- methyl 3-amino-2,2-difluoro-propanoate (CAS 688736-21-2)
- 4-Amino-6-oxo-1,6-dihydropyrimidine-5-carbaldehyde (CAS 1004956-63-1)
Recommended Standards
- 2,5-Difluorobenzonitrile (CAS 64248-64-2)
- 3,4-Difluorobenzonitrile (CAS 64248-62-0)
- 2,4-Difluorophenyl isocyanide (CAS 428818-83-1)
- 2,4-Difluorobenzonitrile (CAS 3939-09-1)
- 8-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 2359716-39-3)
- N-(5-Amino-2-methoxyphenyl)-2-(2-chlorophenoxy)-propanamide (CAS 1020055-19-9)
- 2-Chloro-5-(pyridin-3-yl)oxazole (CAS 1894950-41-4)
- Methyl 4-aminocinnamate (CAS 65198-02-9)
- [1,2,3]Triazolo[1,5-a]pyridine-7-carboxamide (CAS 144675-83-2)
- 7-Methyl-3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 1133-31-9)
- 6-Methoxy-4-oxo-4H-chromene-3-carboxylic acid (CAS 51085-93-9)
- methyl 4-oxo-3H,4H-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (CAS 900783-11-1)
- Sodium ((2R,3S,4R,5R)-5-(4-carbamoylthiazol-2-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogenphosphate (CAS 83091-86-5)
- Uremic Pentapeptide (CAS 71494-20-7)
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