2-(4-Bromo-2-chlorophenoxy)acetic acid CAS 77228-67-2
| CAS No. | 77228-67-2 |
| Molecular Formula | C8H6BrClO3 |
| Molecular Weight | 265.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Bromo-2-chlorophenoxy)acetic acid.
CATO supplies 2-(4-Bromo-2-chlorophenoxy)acetic acid (CAS 77228-67-2), a certified reference material (molecular formula C8H6BrClO3, MW 265.49 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Bromo-2-chlorophenoxy)acetic acid (C8H6BrClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Bromo-2-chlorophenoxy)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrClO3 |
| Molecular Weight | 265.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
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- 5-Bromo-2-chloro-4-methoxybenzoic acid (CAS 1259020-48-8)
- 2-(3-Bromo-4-chlorophenyl)-2-hydroxyacetic acid (CAS 1261552-11-7)
- 2-(2-Bromo-3-chlorophenyl)-2-hydroxyacetic acid (CAS 1261567-99-0)
Recommended Standards
- 2-(2-Bromo-4-chlorophenoxy)acetic acid (CAS 77228-66-1)
- 2-(4-Bromo-3-chlorophenoxy)acetic acid (CAS 90004-81-2)
- methyl 4-bromo-5-chloro-2-hydroxybenzoate (CAS 1935327-46-0)
- 3-Bromo-4-chloro-5-methoxybenzoic acid (CAS 2089300-59-2)
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Why CATO?
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