4-Glutathionyl Cyclophosphamide CAS 77273-67-7
| CAS No. | 77273-67-7 |
| Molecular Formula | C17H30Cl2N5O8PS |
| Molecular Weight | 566.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Glutathionyl Cyclophosphamide (CAS 77273-67-7), molecular formula C17H30Cl2N5O8PS and molecular weight 566.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution, 4-Glutathionyl Cyclophosphamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 566.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Glutathionyl Cyclophosphamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H30Cl2N5O8PS |
| Molecular Weight | 566.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Glutathionyl Standards
Recommended Standards
- Enzalutamide Impurity 48 (CAS CATO-C4X-101648)
- Methyl 2-(4-(2,4-dichlorophenoxy)butanamido)-4-methyl-5-((3-nitrophenyl)carbamoyl)thiophene-3-carboxylate (CAS 335409-25-1)
- (3-Methoxyphenyl)(triphenylphosphine)gold (CAS 870485-34-0)
- Cefazedone Impurity 4 (CAS CATO-C4X-11714)
- 3-Amino-2-(2-(benzo[d]thiazol-2-ylthio)acetyl)but-2-enenitrile (CAS 744230-21-5)
- tert-Butyl (2-(2-amino-N-cyclopropylacetamido)cyclohexyl)carbamate (CAS 1353966-76-3)
- N-(2,3-dimethoxybenzyl)propan-2-amine hydrochloride (CAS 1158345-38-0)
- Furan-2-yl(4-(6-(furan-2-yl)pyridazin-3-yl)piperazin-1-yl)methanone (CAS 923122-85-4)
- (Arg6)-Amyloid β-Protein (1-40) trifluoroacetate salt (CAS 1802084-26-9)
- Methyl 2-(thiazol-2-yl)propanoate (CAS 93472-22-1)
- 4-Chloro-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 1354896-34-6)
- N-Boc-D-serine beta-Lactone (CAS 126330-77-6)
- Beta-Ureido-L-alpha-tosylaminopropionic Acid (CAS 1195628-02-4)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com