2-(2,3-Difluoro-6-methoxyphenyl)-1,3-dioxolane CAS 773087-20-0
| CAS No. | 773087-20-0 |
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,3-Difluoro-6-methoxyphenyl)-1,3-dioxolane (CAS 773087-20-0), molecular formula C10H10F2O3 and molecular weight 216.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,3-Difluoro-6-methoxyphenyl)-1,3-dioxolane (C10H10F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2,3-Difluoro-6-methoxyphenyl)-1,3-dioxolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Difluoro Standards
- Ethyl 3,5-difluoro-2-methoxybenzoate (CAS 1008138-31-5)
- 3-(3,5-Difluoro-4-methoxyphenyl)propanoic acid (CAS 105219-44-1)
- 3-(3,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-64-4)
- 3-(4,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-69-9)
- methyl 4-(2,2-difluoro-1-hydroxyethyl)benzoate (CAS 1176283-75-2)
- 2,4-Difluoro-3-(1-methylethoxy)benzoic acid (CAS 1219020-69-5)
- 2,3-Difluoro-6-nitro-n-propylaniline (CAS 1250052-21-1)
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Recommended Standards
- 1-(1,3-Dimethyl-1h-pyrazol-4-yl)-4,4-difluorobutane-1,3-dione (CAS 758709-42-1)
- 2-(2,4-Difluoro-3-methoxyphenyl)-1,3-dioxolane (CAS 2586126-98-7)
- 2,3-Difluoro-6-isopropoxybenzoic acid (CAS 1917346-66-7)
- 2-(2,4-Difluorophenoxy)-2-methylpropanoic acid (CAS 667413-00-5)
- 4-bromo-3-(difluoromethyl)-5-(trifluoromethyl)aniline (CAS 1805938-42-4)
- Adenine Impurity 16 (CAS 78548-84-2)
- 3-Fluoro-4-(2-isopropylphenoxy)aniline (CAS 946742-35-4)
- 2-((4-Chlorobenzyl)thio)-8-methyl-4H-pyrido[1,2-a][1,3,5]triazin-4-one (CAS 303145-47-3)
- 1-(Bromomethyl)-4-propoxybenzene (CAS 2606-58-8)
- 2,6-Dibromo-3-fluoropyridine (CAS 41404-59-5)
- Sulfasalazine (CAS 599-79-1)
- 9-Methyl-3-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1089342-82-4)
- 2-((2-Amino-6-chloropyrimidin-4-yl)amino)benzoic acid (CAS 18160-09-3)
- Retatrutide (CAS 2381089-83-2)
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