4-Chloro-3,5-bis(trifluoromethyl)benzoic acid CAS 773108-93-3
| CAS No. | 773108-93-3 |
| Molecular Formula | C9H3ClF6O2 |
| Molecular Weight | 292.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 292.56 g/mol gives 4-Chloro-3,5-bis(trifluoromethyl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-3,5-bis(trifluoromethyl)benzoic acid (CAS 773108-93-3), molecular formula C9H3ClF6O2 and molecular weight 292.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-Chloro-3,5-bis(trifluoromethyl)benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 292.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3,5-bis(trifluoromethyl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H3ClF6O2 |
| Molecular Weight | 292.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-4,6-bis(trifluoromethyl)benzoic acid (CAS 916420-47-8)
- 3-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 1902976-00-4)
- 4-Chloro-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole (CAS 2818961-90-7)
- 4-Chloro-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole (CAS 2375917-58-9)
- 4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one (CAS 2490417-60-0)
- 5-Chloro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole (CAS 2377610-32-5)
- 5-Chloro-6-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2768875-63-2)
- 6-Chloro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2377606-80-7)
Recommended Standards
- 3-Bromo-4-chloro-5-methoxy-N,N-dimethylbenzamide (CAS 2089314-87-2)
- 5-Bromo-2-chloro-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine (CAS 942411-03-2)
- Butyl 3-bromo-2-chloroisonicotinate (CAS 2379322-37-7)
- 2-Bromo-N-(5-chloro-2-methoxyphenyl)propanamide (CAS 34836-61-8)
- 1,1'-(2,3-Dimethyl-6-nitro-2,3-dihydroquinoxaline-1,4-diyl)bis(ethan-1-one) (CAS 899374-59-5)
- 3-Methyl-2-(trifluoromethyl)benzofuran (CAS 1099598-16-9)
- (4-(4-Methylpiperazin-1-yl)phenyl)methanamine 2,2,2-trifluoroacetate (CAS 1632286-18-0)
- Ac-Hyp-OH (CAS 33996-33-7)
- 2-(((2-Hydroxypropyl)amino)methyl)-4-methylphenol (CAS 1341539-03-4)
- 3-((2-Aminophenyl)amino)-5-phenylcyclohex-2-en-1-one (CAS 400873-42-9)
- 1-Methyl-3-azabicyclo[3.2.1]octane (CAS 88799-00-2)
- 3-Methoxy-2,2,4-trimethylcyclobutan-1-amine (CAS 1432792-79-4)
- (2R,4R)-1-Cbz-4-methyl-piperidine-2-dicarboxylic acid (CAS 2331211-59-5)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
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