1-Ethynyl-2,4-dimethoxybenzene CAS 77336-36-8
| CAS No. | 77336-36-8 |
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Ethynyl-2,4-dimethoxybenzene (CAS 77336-36-8), molecular formula C10H10O2 and molecular weight 162.19 g/mol, is a CATO reference standard with documented purity and traceability.
1-Ethynyl-2,4-dimethoxybenzene (C10H10O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10O2 |
| Molecular Weight | 162.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Ethynyl Standards
- 2-Ethynyl-1,3-dimethoxybenzene (CAS 126829-31-0)
- 1-Ethynyl-2,3-dimethoxybenzene (CAS 171087-99-3)
- (2-Ethynyl-5-methoxyphenyl)methanol (CAS 89414-50-6)
- 1-Ethynyl-4-methoxymethoxybenzene (CAS 220882-37-1)
- 2-Ethynyl-1,4-dimethoxybenzene (CAS 22944-08-7)
- 1-(2-Ethynyl-4-fluorophenyl)ethan-1-one (CAS 1233506-02-9)
- 1-(3-Ethynyl-4-fluorophenyl)ethan-1-one (CAS 1233513-11-5)
- 6-Ethynyl-2-methyl-3-nitropyridine (CAS 1204333-42-5)
Recommended Standards
- 1-Ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 934605-94-4)
- 1-Ethyl-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 201217-33-6)
- 1-Methoxy-2-(prop-2-yn-1-yloxy)benzene (CAS 41580-71-6)
- 1-Ethyl-1H-benzo[d]imidazol-5-ol (CAS 90868-12-5)
- (R)-4-Bromo-5-chloro-1-(2,2-difluorocyclopropyl)-1H-pyrazole (CAS 2641062-80-6)
- Fmoc-Cys((S)-2,3-di(palmitoyloxy)-propyl)-OH (CAS 139573-78-7)
- 3-Cyclopropoxy-2-(methylsulfonamido)isonicotinic acid (CAS 1243318-50-4)
- 3-Bromo-4-(((2-hydroxyethyl)(methyl)amino)methyl)benzoic acid (CAS 1131594-34-7)
- (Z)-N-(1,1-Dimethoxyhex-5-en-2-ylidene)cyclohexanamine (CAS 62753-24-6)
- N-Methyl-2-(2-(thiophen-2-yl)acetamido)thiophene-3-carboxamide (CAS 921816-03-7)
- 1-Ethyl-1H-1,2,3-triazole-4-sulfonyl chloride (CAS 1393568-12-1)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)aniline (CAS 603117-42-6)
- Methyl 5-(3-isopropoxyphenyl)-5-oxopentanoate (CAS 1443344-64-6)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com