Methyl 3α-trimethylsiloxy-7-keto-5β-cholanate CAS 77341-09-4
| CAS No. | 77341-09-4 |
| Molecular Formula | C28H48O4Si |
| Molecular Weight | 476.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3α-trimethylsiloxy-7-keto-5β-cholanate.
CATO supplies Methyl 3α-trimethylsiloxy-7-keto-5β-cholanate (CAS 77341-09-4), a certified reference material (molecular formula C28H48O4Si, MW 476.76 g/mol) for analytical method development and quality control.
Based on its molecular formula C28H48O4Si, Methyl 3α-trimethylsiloxy-7-keto-5β-cholanate contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 476.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H48O4Si |
| Molecular Weight | 476.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Methyl Standards
- 17beta-(Trimethylsiloxy)testosterone (CAS 5055-42-5)
- Tris(trimethylsiloxy)silane (CAS 1873-89-8)
- Bis(trimethylsiloxy)methylmethoxysilane (CAS 7671-19-4)
- 1,2-Bis(trimethylsiloxy)ethane 2,2,7,7-Tetramethyl-3,6-dioxa-2,7-disilaoctane 1,3-bis(trimethylsiloxy)ethane Ethylene glycol bis(trimethylsilyl ether) 1,2-Bis-trimethylsilanyloxy-ethane ethylenedioxybis(trimethylsilane) 1,2-bis(trimethylsilyloxy)ethane ethylenedioxybistrimethylsilane 1,2 bis(trimethylsilyloxy) ethane 1,2-bis-(trimethylsilyloxy)ethane 7381-30-8 S02325 (CAS 7381-30-8)
- 2-(Trimethylsiloxy)ethylmethacrylate (CAS 17407-09-9)
- Tris(trimethylsiloxy)ethylene (CAS 24858-02-4)
Recommended Standards
- 5-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one (CAS 337921-05-8)
- Mmucpp (CAS 93134-82-8)
- 2,2'-Thiobis(N,N-dicyclohexylacetamide) (CAS 849629-03-4)
- Obeticholic Acid Impurity 43 (CAS CATO-C4X-115343)
- 2-Bromo-N-(3,4-dichlorophenyl)butanamide (CAS 1339178-53-8)
- 4-Bromo-2-cyano-3-(difluoromethyl)pyridine-6-carboxaldehyde (CAS 1805371-09-8)
- 3-Chloro-N-(4-methoxyphenyl)benzamide (CAS 158525-81-6)
- Methyl pentylglycinate (CAS 1020971-29-2)
- 5-[3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-1,2-dihydropyridin-2-one (CAS 1239843-30-1)
- 3-(3,5-dimethyl-1H-pyrazol-4-yl)prop-2-ynoic acid (CAS 1351382-56-3)
- N-(4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl)acetamide (CAS 58107-05-4)
- 1-(Allyloxy)-4-bromo-2-fluorobenzene (CAS 1332355-03-9)
- 4-O-(b-D-Galactopyranosyl)-D-galactopyranose (CAS 2152-98-9)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com