5-(Bromomethyl)-3-(3-(trifluoromethyl)phenyl)isoxazole CAS 77362-82-4
| CAS No. | 77362-82-4 |
| Molecular Formula | C11H7BrF3NO |
| Molecular Weight | 306.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Bromomethyl)-3-(3-(trifluoromethyl)phenyl)isoxazole.
5-(Bromomethyl)-3-(3-(trifluoromethyl)phenyl)isoxazole (CAS 77362-82-4) is a high-purity analytical reference standard with the molecular formula C11H7BrF3NO and a molecular weight of 306.08 g/mol.
5-(Bromomethyl)-3-(3-(trifluoromethyl)phenyl)isoxazole (C11H7BrF3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7BrF3NO |
| Molecular Weight | 306.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 5-(Bromomethyl)-3-(4-(trifluoromethyl)phenyl)isoxazole (CAS 66046-45-5)
- Ethyl 2-(bromomethyl)-5-fluoro-4-nitrobenzoate (CAS 2102177-39-7)
- 1-[3,5-Bis(bromomethyl)phenyl]-ethanone (CAS 544467-01-8)
- 2-(Bromomethyl)-3-(phenylsulfonyl)-1,3-oxazolidine (CAS 1172514-18-9)
- 2,5-bis(bromomethyl)-1,4-dioxane-2,5-diol (CAS 23386-71-2)
- 4-(Bromomethyl)-9-chloroacridine (CAS 15971-23-0)
- 4'-(Bromomethyl)-3'-chloro-[1,1'-biphenyl]-2-carbonitrile (CAS 887268-24-8)
- (5-(Bromomethyl)-2-chlorophenyl)(trifluoromethyl)sulfane (CAS 886503-38-4)
Recommended Standards
- 4-Bromo-5-methoxy-2-(trifluoromethyl)quinoline (CAS 587885-89-0)
- 4-[4-bromo-3-(trifluoromethyl)-1H-pyrazol-1-yl]aniline (CAS 2044722-54-3)
- 6-Bromo-4-methoxy-2-(trifluoromethyl)quinoline (CAS 882292-61-7)
- 3-Bromo-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridine (CAS 2432849-17-5)
- 3-((Naphthalen-2-yloxy)methyl)benzohydrazide (CAS 438474-99-8)
- Benzyltriethylphosphonium chloride (CAS 23666-92-4)
- 5-(Chloromethyl)imidazo[1,2-a]pyridine (CAS 167884-16-4)
- 3-Bromo-2-methyl-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 478248-99-6)
- tert-Butyl 4-((6-methoxy-2-(methylthio)pyrimidin-4-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1353987-55-9)
- 21216-78-4 1V3IY31A0T Diphenylpiperidinomethyldioxolan iodide [JAN] N-(2,2-Diphenyl-1,3-dioxolanyl-4-methyl)piperidium methyl iodide Piperidinium, 1-(2,2-diphenyl-1,3-dioxolan-4-ylmethyl)-1-methyl-, iodide 1-(2,2-Diphenyl-1,3-dioxolan-4-ylmethyl)-1-methylpiperidinium iodide ANC-53 2,2-Diphenyl-4-piperidinomethyl-dioxolane-1,3 methiodide Anacolin UNII-1V3IY31A0T Diphenylpiperidinomethyldioxolan iodide (CAS 21216-78-4)
- Benzyl 2,3-dibromopropanoate (CAS 10288-11-6)
- 6-Iodo-4-methoxy-2,2'-bipyridine (CAS 205052-94-4)
- 2-(CYclopentyloxy)-3-nitropyridine (CAS 1394966-72-3)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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