[4-(difluoromethoxy)-3-ethoxyphenyl]methanol CAS 773868-64-7

Description

Compared with other compounds in its class, the molecular weight of 218.20 g/mol gives [4-(difluoromethoxy)-3-ethoxyphenyl]methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

[4-(difluoromethoxy)-3-ethoxyphenyl]methanol (CAS 773868-64-7), molecular formula C10H12F2O3 and molecular weight 218.20 g/mol, is a CATO reference standard with documented purity and traceability.

[4-(difluoromethoxy)-3-ethoxyphenyl]methanol (C10H12F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [4-(difluoromethoxy)-3-ethoxyphenyl]methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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