Pethidine EP Impurity A CAS 774-52-7
| CAS No. | 774-52-7 |
| Molecular Formula | C12H17N |
| Molecular Weight | 175.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pethidine EP Impurity A.
CATO supplies Pethidine EP Impurity A (CAS 774-52-7), a pharmacopoeial impurity reference standard (molecular formula C12H17N, MW 175.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Pethidine EP Impurity A (C12H17N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17N |
| Molecular Weight | 175.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Pethidine Standards
- Pethidine EP Impurity B (CAS 28289-54-5)
- Pethidine Impurity 1 (CAS 51281-64-2)
- Pethidine impurity 10 (CAS CATO-C4X-223210)
- Pethidine Impurity 3 (CAS 158984-76-0)
- Pethidine Impurity 6 (CAS 6094-60-6)
- Pethidine Impurity 2 (CAS 79858-48-3)
- Pethidine Hydrochloride EP Impurity C (CAS CATO-C4X-22324)
- Pethidine Impurity 4 (CAS 92197-36-9)
Recommended Standards
- Selexipag Impurity 34 (CAS CATO-C4X-196134)
- Sulforaphene (CAS 592-95-0)
- Amifostine Impurity 9 (CAS 17002-55-0)
- N-methyl-1-(p-tolyl)cyclobutan-1-amine (CAS 1510522-81-2)
- Tamsulosin Impurity 77 (CAS 1510621-28-9)
- Ruxolitinib Impurity 29 (CAS CATO-C4X-205829)
- Baricitinib Impurity 6 (CAS 2271228-51-2)
- 5-(3-Chloro-phenyl)-4-(4-ethoxy-phenyl)-4H-[1,2,4]triazole-3-thiol (CAS 519151-97-4)
- n-Benzyl-2-hydroxy-4-methoxybenzamide (CAS 610320-51-9)
- 2,6-Di-tert-butyl-4-methylphenol D21 (CAS 64502-99-4)
- 2-(2,6-Dichloropyridin-3-yl)-5-methyl-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431727-96-6)
- 2-(2-Methoxyphenyl)oxazolo[4,5-b]pyridine (CAS 52333-62-7)
- Daclatasvir Impurity 4 (CAS 1009113-58-9)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com