(2R,4S)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid CAS 77449-97-9
| CAS No. | 77449-97-9 |
| Molecular Formula | C7H11NO4 |
| Molecular Weight | 173.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2R,4S)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid (CAS 77449-97-9), molecular formula C7H11NO4 and molecular weight 173.17 g/mol, is a CATO reference standard with documented purity and traceability.
(2R,4S)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid (C7H11NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (2R,4S)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H11NO4 |
| Molecular Weight | 173.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2R,4R)-Ethyl 4-hydroxy-5-oxopyrrolidine-2-carboxylate (CAS 455334-20-0)
- (2R,4S)-piperidine-2,4-dicarboxylic acid (CAS 84211-45-0)
- (2R,4R)-4-Methylpyrrolidine-2,4-dicarboxylic acid (CAS 403857-35-2)
- (2R,5S)-1-Methylpyrrolidine-2,5-dicarboxylic acid (CAS 52321-05-8)
- 2-(Benzyloxy)-N-ethylethanamine (CAS 104678-17-3)
- (R)-Methyl 2-acetamidopropanoate (CAS 19914-36-4)
- N-(4-Methoxyphenyl)-2-(pyridin-2-ylsulfanyl)acetamide (CAS 298215-17-5)
- 3-Chloro-2-((1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)-5-(trifluoromethyl)pyridine (CAS 306978-32-5)
- 2-((4-Chloro-6-(methylamino)pyrimidin-5-yl)methyl)benzoic acid (CAS 64261-36-5)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(2-hydroxyphenyl)propanoic acid (CAS 1213668-39-3)
- 2-((4-(Trifluoromethyl)phenyl)amino)-1H-purin-6(9H)-one (CAS 123994-74-1)
- (2R)-1-(morpholin-4-yl)propan-2-ol (CAS 65617-06-3)
- 1-(Bromomethyl)-2,4-difluoro-3-(trifluoromethoxy)benzene (CAS 2149591-35-3)
- Smac-N7 Peptide (CAS 401913-57-3)
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