1-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carbohydrazide CAS 774575-27-8
| CAS No. | 774575-27-8 |
| Molecular Formula | C13H19N3O4S |
| Molecular Weight | 313.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carbohydrazide (CAS 774575-27-8) is a high-purity analytical reference standard with the molecular formula C13H19N3O4S and a molecular weight of 313.37 g/mol.
The molecular framework of 1-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carbohydrazide (C13H19N3O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H19N3O4S |
| Molecular Weight | 313.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 1-[(4-Ethoxybenzene)sulfonyl]piperidine-4-carboxylic acid (CAS 757220-86-3)
- 1-{6-[4-(4-fluorophenyl)piperazin-1-yl]-2-methylpyridin-3-yl}ethan-1-one (CAS 478260-06-9)
- 1-(4-Isopropoxybenzoyl)benzo[c]isothiazol-3(1H)-one (CAS 877811-74-0)
- 1-Isopropyl-4-((4-nitrophenyl)sulfonyl)piperazine (CAS 519006-12-3)
- 5'-(methylsulfanyl)-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (CAS 83414-17-9)
- Grubbs Catalyst<SUP>®</SUP> M310 (CAS 1031262-76-6)
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- 5-methyl-1H-pyrazolo[4,3-b]pyridine (CAS 52090-69-4)
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