1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-4-ol CAS 77458-38-9
| CAS No. | 77458-38-9 |
| Molecular Formula | C10H7F3N2O |
| Molecular Weight | 228.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-4-ol (CAS 77458-38-9), a certified reference material (molecular formula C10H7F3N2O, MW 228.17 g/mol) for analytical method development and quality control.
The molecular framework of 1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-4-ol (C10H7F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-[3-(trifluoromethyl)phenyl]-1h-pyrazol-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2O |
| Molecular Weight | 228.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 6-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)pyridin-3-amine (CAS 1006464-92-1)
- 1-(4-(Trifluoromethyl)phenyl)-1H-pyrazol-3-ol (CAS 1020058-01-8)
- 3-(6-(Trifluoromethyl)pyridin-3-yl)-1H-pyrazol-5-amine (CAS 1040724-49-9)
- 1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazol-5-amine (CAS 107748-59-4)
- 2-Methyl-8-(trifluoromethyl)quinazolin-4(3H)-one (CAS 1112985-71-3)
- 1-(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)ethan-1-one (CAS 1134395-17-7)
- 6-Methyl-7-(trifluoromethyl)quinazolin-4-ol (CAS 1160994-09-1)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1172234-58-0)
Recommended Standards
- 1,1,1-Trifluoro-4-(4-methoxyphenyl)but-3-yn-2-one (CAS 89965-74-2)
- 1-Hydroxy-4-(trifluoromethoxy)cyclohexane-1-carboxylic acid (CAS 2231676-89-2)
- (4-Bromo-Phenoxy)-Difluoro-Acetic Acid Ethyl Ester (CAS 807368-45-2)
- 1-methyl-5-(trifluoromethyl)benzimidazole-2-carbaldehyde (CAS 958863-77-9)
- 7-(4-Ethylpiperazin-1-yl)-2,5-dimethyl-3-(p-tolyl)pyrazolo[1,5-a]pyrimidine (CAS 902008-80-4)
- Betazole DiHCl (CAS 138-92-1)
- Rac-(1r,2r,3s,4s)-3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid hydrochloride (CAS 947601-81-2)
- 2-(Difluoromethyl)-6-fluoro-4-iodopyridine-3-acetic acid (CAS 1805053-82-0)
- Ethyl 5-amino-3-ethyl-1-(2-hydroxy-2-phenylethyl)-1H-pyrazole-4-carboxylate (CAS 1638612-77-7)
- (R)-2-Amino-3-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)propanoic acid (CAS 95758-95-5)
- N-Nitroso-N-methyl-DL-phenylalanine (CAS 41867-08-7)
- (R)-Benzyl 3-(2-chloroacetamido)pyrrolidine-1-carboxylate (CAS 1353995-06-8)
- 4,4-Dimethoxyoctafluorobiphenyl (CAS 2200-71-7)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
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