Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate CAS 77505-90-9
| CAS No. | 77505-90-9 |
| Molecular Formula | C12H11ClN2O2S |
| Molecular Weight | 282.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.75 g/mol gives Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate (CAS 77505-90-9) is a high-purity analytical reference standard with the molecular formula C12H11ClN2O2S and a molecular weight of 282.75 g/mol.
Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate (C12H11ClN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 2-amino-5-(3-chlorophenyl)thiazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O2S |
| Molecular Weight | 282.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- ethyl 2-amino-4-(4-chlorophenyl)thiazole-5-carboxylate (CAS 74476-53-2)
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- n-(3-Aminophenyl)-4-chlorobenzene-1-sulfonamide (CAS 953733-67-0)
- 4-(((4-Bromophenyl)imino)methyl)-N,N-dimethylaniline (CAS 15485-29-7)
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- Methyl 2-((1H-imidazol-4-yl)methylene)hydrazinecarbodithioate (CAS 68282-63-3)
- 2-Amino-5-cyclopropoxypyridine-4-sulfonamide (CAS 1243399-19-0)
- Lansoprazole EP Impurity A (CAS 213476-12-1)
- 3'-Fluoro-4'-methyl-[1,1'-biphenyl]-3-carbaldehyde (CAS 885964-68-1)
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- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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