2-(4-Bromo-1H-pyrazol-1-yl)-5-nitropyridine CAS 77556-30-0

Purity 97%+In StockPharmaceutical Standards
CAS No.77556-30-0
Molecular FormulaC8H5BrN4O2
Molecular Weight269.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Bromo-1H-pyrazol-1-yl)-5-nitropyridine CAS 77556-30-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Bromo-1H-pyrazol-1-yl)-5-nitropyridine.

CATO supplies 2-(4-Bromo-1H-pyrazol-1-yl)-5-nitropyridine (CAS 77556-30-0), a certified reference material (molecular formula C8H5BrN4O2, MW 269.05 g/mol) for analytical method development and quality control.

2-(4-Bromo-1H-pyrazol-1-yl)-5-nitropyridine (C8H5BrN4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H5BrN4O2
Molecular Weight269.05 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentBr-containing
Nitrogen Atoms4

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