2-(2-(o-Tolyl)-1H-imidazol-4-yl)ethanamine CAS 776235-56-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(o-Tolyl)-1H-imidazol-4-yl)ethanamine.

2-(2-(o-Tolyl)-1H-imidazol-4-yl)ethanamine (CAS 776235-56-4), molecular formula C12H15N3 and molecular weight 201.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2-(o-Tolyl)-1H-imidazol-4-yl)ethanamine (C12H15N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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