2,6-Diamino-5-mercaptopyrimidin-4(1H)-one CAS 77708-93-1
| CAS No. | 77708-93-1 |
| Molecular Formula | C4H6N4OS |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Diamino-5-mercaptopyrimidin-4(1H)-one (CAS 77708-93-1), molecular formula C4H6N4OS and molecular weight 158.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,6-Diamino-5-mercaptopyrimidin-4(1H)-one (C4H6N4OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6N4OS |
| Molecular Weight | 158.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Diamino Standards
- 4,5-diamino-2-thiouracil (CAS 1004-76-8)
- 1246816-80-7 5,6-Diamino-2-thiouracil-13C,15N (CAS 1246816-80-7)
- 1346601-57-7 5,6-Diamino-4-thiouracil-13C2 (CAS 1346601-57-7)
- 5,6-Diamino-4-thioxo-3,4-dihydropyrimidin-2(1H)-one (CAS 40848-33-7)
- 4,5-Diamino-1-(2-hydroxyethyl)-1H-pyrazol-3(2H)-one (CAS 175700-82-0)
- 2-((3,4-Diamino-1H-pyrazol-1-yl)oxy)ethanol (CAS 927417-33-2)
- 2-((4,5-Diamino-1H-pyrazol-1-yl)oxy)ethanol (CAS 927417-22-9)
- 5,6-Diamino-3-methyldihydropyrimidine-2,4(1H,3H)-dione (CAS 474096-64-5)
Recommended Standards
- 2,5-Dioxopyrrolidine-1-carbothioamide (CAS 37454-84-5)
- 2-[(1,3-Thiazol-2-yl)amino]acetic acid (CAS 79858-47-2)
- 2,3-dihydro-2-thioxo-1H-Imidazole-4-carboxylic acid methyl ester (CAS 57332-70-4)
- 2-Amino-4-methylthiazole-5-carboxylic acid (CAS 67899-00-7)
- N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide HCl (CAS 61714-27-0)
- (3S,7S)-3,7-Dimethylnonane-4,6-dione (CAS 34865-74-2)
- decahydronaphthalen-2-amine (CAS 18649-65-5)
- (Tetrahydrofuran-2-yl)methyl 3-oxobutanoate (CAS 7249-93-6)
- Methyl 4-bromo-3a,7a-dihydro-1H-indole-6-carboxylate (CAS 2764702-73-8)
- (R)-Methyl 2-amino-3-(pyridin-2-yl)propanoate dihydrochloride (CAS 163513-22-2)
- 3-(2,5-Dichlorothiophen-3-yl)-1H-pyrazole (CAS 166196-62-9)
- 2-(2-Nitroethyl)-N'-(pyridin-2-yl)benzohydrazide (CAS 338410-34-7)
- (4-Nitrophenyl)(tetrahydropyridazin-1(2H)-yl)methanone (CAS 443295-30-5)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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