(8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone CAS 77771-22-3

Purity 97%+In StockPharmaceutical Standards
CAS No.77771-22-3
Molecular FormulaC15H14N2O2
Molecular Weight254.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone CAS 77771-22-3 chemical structure

Description

CATO supplies (8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone (CAS 77771-22-3), a certified reference material (molecular formula C15H14N2O2, MW 254.28 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, (8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 254.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H14N2O2
Molecular Weight254.28 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms2

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