2-Amino-N-(3-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide CAS 777876-93-4
| CAS No. | 777876-93-4 |
| Molecular Formula | C17H19ClN2OS |
| Molecular Weight | 334.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Amino-N-(3-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Amino-N-(3-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (CAS 777876-93-4) is a high-purity analytical reference standard with the molecular formula C17H19ClN2OS and a molecular weight of 334.86 g/mol.
The molecular framework of 2-Amino-N-(3-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (C17H19ClN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2OS |
| Molecular Weight | 334.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-N-(2-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (CAS 726144-24-7)
- 2-Amino-N-(4-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (CAS 669740-02-7)
- 2-Amino-N-(4-chlorophenyl)-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide (CAS 669738-72-1)
- N-(5-Amino-2-methoxyphenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020054-26-5)
- N-(3-Amino-4-chlorophenyl)-4-(2-ethoxyethoxy)-benzamide (CAS 1020054-56-1)
- N-(3-Amino-4-chlorophenyl)-2-(2-ethoxyethoxy)-benzamide (CAS 1020054-59-4)
- N-(3-Amino-4-chlorophenyl)-3-(2-ethoxyethoxy)-benzamide (CAS 1020054-65-2)
- 2-Amino-5-(3-((4-(2-chloroacetyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-51-6)
Recommended Standards
- 1-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-2-(thiophen-2-yl)ethan-1-one (CAS 639810-40-5)
- 1-(7-(2-Chlorophenyl)-1,4-thiazepan-4-yl)-2-(1H-pyrrol-1-yl)ethan-1-one (CAS 1798672-21-5)
- 3-Hydroxy Chlorpromazine (CAS 3930-47-0)
- 10-Chloro-7,7-dimethyl-7H-benzo[b]fluoreno[3,4-d]thiophene (CAS 1616706-34-3)
- 2-Chloro-1-methyl-1H-imidazo[4,5-b]pyridine (CAS 65550-24-5)
- isoalantolactone (CAS 470-17-7)
- 2-(4-Chloropyrimidin-5-yl)acetic acid (CAS 389799-46-6)
- (3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)boronic acid (CAS 1246765-28-5)
- 3-Chloro-6-fluoro-1-benzothiophene-2-carbonyl chloride (CAS 34576-83-5)
- 5-Chloro-7-fluoro-2,3-dihydro-1h-indole-2,3-dione (CAS 953894-64-9)
- 2,2,3,3,3-Pentafluoro-1-(5-fluoro-2-methoxyphenyl)propan-1-one (CAS 1352208-76-4)
- tert-butyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl(methyl)carbamate (CAS 1420983-60-3)
- α-D-Glucopyranose-1- (CAS 478518-99-9)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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