methyl 2-chloro-5-nitro-pyridine-4-carboxylate CAS 777899-57-7
| CAS No. | 777899-57-7 |
| Molecular Formula | C7H11ClN2O4 |
| Molecular Weight | 222.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
methyl 2-chloro-5-nitro-pyridine-4-carboxylate (CAS 777899-57-7) is a high-purity analytical reference standard with the molecular formula C7H11ClN2O4 and a molecular weight of 222.63 g/mol.
Based on its molecular formula C7H11ClN2O4, methyl 2-chloro-5-nitro-pyridine-4-carboxylate contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11ClN2O4 |
| Molecular Weight | 222.63 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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- 2-Cyclohexen-1-one, 3-chloro-5,5-dimethyl- (CAS 17530-69-7)
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- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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