5-Chloro-2-(trifluoromethoxy)benzene-1-sulfonyl chloride CAS 77797-64-9
| CAS No. | 77797-64-9 |
| Molecular Formula | C7H3Cl2F3O3S |
| Molecular Weight | 295.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-(trifluoromethoxy)benzene-1-sulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 77797-64-9), a certified reference material (molecular formula C7H3Cl2F3O3S, MW 295.06 g/mol) for analytical method development and quality control.
Structurally, 5-Chloro-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (C7H3Cl2F3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 295.06 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3Cl2F3O3S |
| Molecular Weight | 295.06 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-(trifluoromethoxy)benzenesulfonyl chloride (CAS 748163-14-6)
- 2-Chloro-5-(4-Chloro-3,5-Difluorophenyl)-1,3-Difluorobenzene (CAS 75795-05-0)
- 3-Chloro-4-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 886762-48-7)
- Methyl 2-chloro-6-((2-chloroethyl)amino)-5-nitropyrimidine-4-carboxylate (CAS 98546-07-7)
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Recommended Standards
- 4-Bromo-6-methoxy-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1980045-57-5)
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- 3-Bromo-2-(trifluoromethyl)-6,6a,7,7a-tetrahydro-4H-cyclopropa[3,4]pyrrolo[1,2-a]pyrimidin-4-one (CAS 2648792-82-7)
- 1-(Chloromethyl)-3-(3-fluorophenyl)bicyclo[1.1.1]Pentane (CAS 2287344-70-9)
- 9,10-Di(pyridin-4-yl)anthracene (CAS 194861-72-8)
- 2-Dodecyltetradecanoic Acid Methyl Ester (CAS 167083-39-8)
- 2-Phenylmalondialdehyde (CAS 26591-66-2)
- 5-Amino-2-(5,6-dimethylbenzo[d]oxazol-2-yl)phenol (CAS 310414-52-9)
- Parishin C (CAS 174972-80-6)
- 1-Bromo-4-[(phenylsulfinyl)methyl]benzene (CAS 100375-00-6)
- 2-Methylbicyclo[2.2.1]heptane-2-carbaldehyde (CAS 62255-33-8)
- 3-(4-methoxyphenyl)imidazolidine-2,4-dione (CAS 62101-55-7)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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