2-Amino-5-bromo-4,6-dichloropyrimidine CAS 7781-26-2

Purity 97%+In StockPharmaceutical Standards
CAS No.7781-26-2
Molecular FormulaC4H2BrCl2N3
Molecular Weight242.89 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-5-bromo-4,6-dichloropyrimidine CAS 7781-26-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 242.89 g/mol gives 2-Amino-5-bromo-4,6-dichloropyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Amino-5-bromo-4,6-dichloropyrimidine (CAS 7781-26-2), a certified reference material (molecular formula C4H2BrCl2N3, MW 242.89 g/mol) for analytical method development and quality control.

The molecular framework of 2-Amino-5-bromo-4,6-dichloropyrimidine (C4H2BrCl2N3) is characterized by a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Amino-5-bromo-4,6-dichloropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H2BrCl2N3
Molecular Weight242.89 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1959
Halogen ContentCl/Br-containing
Nitrogen Atoms3

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