Edoxaban Impurity N4 CAS 778571-11-2
| CAS No. | 778571-11-2 |
| Molecular Formula | C23H28ClN7O4S |
| Molecular Weight | 534.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Edoxaban Impurity N4 (C23H28ClN7O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Edoxaban Impurity N4 (CAS 778571-11-2, C23H28ClN7O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Edoxaban Impurity N4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28ClN7O4S |
| Molecular Weight | 534.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban Impurity N7 (CAS 740794-83-6)
- Edoxaban impurity 132 (CAS CATO-C4X-1063132)
- Edoxaban Impurity 142 (CAS CATO-C4X-1063142)
- Edoxaban Impurity 6 (CAS CATO-C4X-10636)
- Edoxaban Impurity 118 (CAS CATO-C4X-1063118)
- Edoxaban Impurity 119 (CAS CATO-C4X-1063119)
- Edoxaban Impurity 121 (CAS CATO-C4X-1063121)
- Edoxaban Impurity 17 (CAS 834919-19-6)
Recommended Standards
- 3,4,5-Tris(4-bromophenyl)-4H-1,2,4-triazole (CAS 920984-66-3)
- Rivaroxaban Impurity 76 (CAS 2305917-61-5)
- Pyronaridine Impurity 4 (CAS CATO-C4X-29784)
- Olodaterol Impurity 19 (CAS CATO-C4X-194319)
- Candesartan Cilexetil Impurity 31 (CAS CATO-C4X-123431)
- Ticagrelor Impurity 114 (CAS CATO-C4X-1093114)
- Norfloxacin Impurity 59 (CAS CATO-C4X-146859)
- (2-(4-Benzylpiperazin-1-yl)pyridin-4-yl)methanamine (CAS 1156349-84-6)
- 5-N-phenylpyridine-2,5-diamine (CAS 79441-22-8)
- Methyl 2-chloro-2-(5-chloro-2-methoxy-3-methylphenyl)acetate (CAS 94242-10-1)
- 3-Phenyl-1-(piperidin-4-yl)propan-1-ol (CAS 24152-52-1)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-chloro-2-cyclopropylphenyl)boronate (CAS 2223040-59-1)
- 2,2,6-Trimethyl-1,2,3,4-tetrahydroquinolin-3-ol (CAS 828939-16-8)
- [D-Glu]3-Semaglutide (CAS CATO-C4X-2226253)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com