N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-8-(methylsulfonamido)dibenzo[b,d]furan-1-carboxamide CAS 778576-62-8
| CAS No. | 778576-62-8 |
| Molecular Formula | C20H13Cl2F2N3O5S |
| Molecular Weight | 516.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-8-(methylsulfonamido)dibenzo[b,d]furan-1-carboxamide.
CATO supplies N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-8-(methylsulfonamido)dibenzo[b,d]furan-1-carboxamide (CAS 778576-62-8), a certified reference material (molecular formula C20H13Cl2F2N3O5S, MW 516.30 g/mol) for analytical method development and quality control.
N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-8-(methylsulfonamido)dibenzo[b,d]furan-1-carboxamide (C20H13Cl2F2N3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-8-(methylsulfonamido)dibenzo[b,d]furan-1-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H13Cl2F2N3O5S |
| Molecular Weight | 516.30 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(3,5-Dichloropyridin-4-yl)-2-[1-(4-fluorobenzyl)-5-hydroxy-1H-indol-3-yl]-2-oxo-acetamide (CAS 257892-33-4)
- (2,6-Dichloropyridin-4-yl)methyl (3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)carbamate (CAS 261622-75-7)
- (E)-2-(4-(2-(5-(1-(3,5-DICHLOROPYRIDIN-4-YL)ETHOXY)-1H-INDAZOL-3-YL)VINYL)-1H-PYRAZOL-1-YL)ETHANOL (CAS 1254473-85-2)
- N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazine-1-carboxamide (CAS 383150-41-2)
- 2-((3,5-Dichloropyridin-2-yl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 502860-56-2)
- Ethyl 2-((5-(2,6-dichloropyridin-4-yl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetate (CAS 680216-57-3)
- N-(2-(3,5-Dichloropyridin-2-yl)phenyl)-2-methylfuran-3-carboxamide (CAS 824952-75-2)
- N'-((2,6-dichloropyridin-3-yl)methylene)-4-methylbenzenesulfonohydrazide (CAS 1820748-57-9)
Recommended Standards
- 3-Bromo-2,5-difluoro-N,N-bis(4-methoxybenzyl)-4-(trifluoromethyl)aniline (CAS 2852766-96-0)
- (2-Oxopropyl)(triphenylphosphine)gold (CAS 40757-39-9)
- 2-(2,6-dioxo-3-piperidyl)-4-[2-[2-(2-iodoethoxy)ethoxy]ethoxy]isoindoline-1,3-dione (CAS 2349356-56-3)
- 1,1-[Ethylidenebis(2,3-dichloro-4,1-phenylene)]bis[4-methyl-piperazine (CAS 519138-47-7)
- Methyl (6-chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate (CAS 500203-85-0)
- 2-(3,4,5-Trifluorophenyl)pyridine (CAS 511522-81-9)
- (4S)-3-(1-Oxohexyl)-4-(phenylmethyl)-2-oxazolidinone (S)-4-Benzyl-3-hexanoyl-2-oxazolidinone (S)-4-Benzyl-3-hexanoyloxazolidin-2-one 143965-32-6 (CAS 143965-32-6)
- Bortezomib Impurity 60 (CAS CATO-C4X-107260)
- 2-Bromo-n-(3-fluorophenyl)benzenesulfonamide (CAS 851215-82-2)
- 3-Methyl-4-(m-tolyl)azetidin-2-one (CAS 1864295-42-0)
- 1-(1,3-Dimethyl-1h-1,2,4-triazol-5-yl)propan-1-amine (CAS 1250155-36-2)
- 7,8-Dimethoxyphthalazin-1-amine (CAS 1706429-30-2)
- 2-(5-Methyl-1H-indol-3-yl)ethylamine hydrochloride 2-(5-methyl-1H-indol-3-yl)ethanamine hydrochloride 55795-89-6 (CAS 55795-89-6)
- C-Peptide (human) (CAS 33017-11-7)
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