5-Amino-6-chloro-2,3-dihydro-1h-indol-2-one CAS 77859-59-7
| CAS No. | 77859-59-7 |
| Molecular Formula | C8H7ClN2O |
| Molecular Weight | 182.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 182.61 g/mol gives 5-Amino-6-chloro-2,3-dihydro-1h-indol-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Amino-6-chloro-2,3-dihydro-1h-indol-2-one (CAS 77859-59-7) is a high-purity analytical reference standard with the molecular formula C8H7ClN2O and a molecular weight of 182.61 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Amino-6-chloro-2,3-dihydro-1h-indol-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2O |
| Molecular Weight | 182.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-5-chloro-1,3-dihydro-2H-indol-2-onehydrochloride (CAS 1104895-64-8)
- 2-Amino-8-chloro-6-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1313712-48-9)
- 2-Amino-6-chloro-8-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1319067-92-9)
- 4-Amino-3-chloro-2-methoxybenzonitrile (CAS 1362077-38-0)
- 5-Amino-6-chloroisoindolin-1-one (CAS 1367864-25-2)
- 7-Amino-5-chloroindolin-2-one (CAS 1368708-97-7)
- 6-Amino-5-chloro-2,3-dihydro-1H-indol-2-one (CAS 1379362-72-7)
- 4-Amino-2-chloro-5-methoxybenzonitrile (CAS 1613730-68-9)
Recommended Standards
- 5-(Cyanomethyl)-1-methyl-1H-pyrrole-2-carbonyl chloride (CAS 52074-59-6)
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- 5-(Chloromethyl)benzo[d]oxazol-2-amine (CAS 947765-03-9)
- 5-Chloro-1-methyl-1,3-dihydro-2H-pyrrolo[2,3-c]pyridin-2-one (CAS 2306276-30-0)
- (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic Acid (CAS 1180676-33-8)
- N-Hexylethylenediamine (CAS 7261-70-3)
- (R)-4-(4,6-Dichloro-1,3,5-triazin-2-yl)-3-methylmorpholine (CAS 1382088-39-2)
- 4-Deoxy-D-xylo-hexopyranose (CAS 28434-38-0)
- 352530-35-9 5-Bromo-2-methoxybenzylzinc chloride, 0.5M in tetrahydrofuran MFCD02260144 (CAS 352530-35-9)
- tert-Butyl 4-(2-chloro-6-methylpyrimidin-4-yl)-3-methylpiperazine-1-carboxylate (CAS 1261235-51-1)
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- 1-(1-benzothiophen-2-yl)ethan-1-amine hydrochloride (CAS 1803593-05-6)
- 3-[(2-aminophenyl)formamido]propanamide (CAS 1156868-60-8)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
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