Methyl 5-amino-3-chloro-4-methylthiophene-2-carboxylate CAS 778611-10-2
| CAS No. | 778611-10-2 |
| Molecular Formula | C7H8ClNO2S |
| Molecular Weight | 205.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 5-amino-3-chloro-4-methylthiophene-2-carboxylate (CAS 778611-10-2), a certified reference material (molecular formula C7H8ClNO2S, MW 205.66 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 5-amino-3-chloro-4-methylthiophene-2-carboxylate (C7H8ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 5-amino-3-chloro-4-methylthiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO2S |
| Molecular Weight | 205.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- (R)-2-amino-3-(5-chlorothiophen-2-yl)propanoic acid (CAS 1151862-89-3)
- (r)-3-Amino-3-(5-chlorothiophen-2-yl)propanoic acid (CAS 1270060-15-5)
- (r)-3-Amino-3-(4-chlorothiophen-2-yl)propanoic acid (CAS 1366284-77-6)
- (s)-3-Amino-3-(4-chlorothiophen-2-yl)propanoic acid (CAS 1366563-92-9)
- 2-Amino-3-(4-chlorothiophen-2-yl)propanoic acid (CAS 1539705-03-7)
- 3-Amino-3-(4-chlorothiophen-2-yl)propanoic acid (CAS 194229-24-8)
- (S)-2-amino-2-(5-chlorothiophen-2-yl)propanoic acid (CAS 68056-35-9)
- (S)-2-amino-3-(5-chlorothiophen-2-yl)propanoic acid (CAS 911471-88-0)
Recommended Standards
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- n-(3-Chlorophenyl)methanesulfonamide (CAS 7022-21-1)
- 2-(2-Bromophenyl)-N-(2-hydroxyethyl)acetamide (CAS 855927-64-9)
- Ethyl 6-(chloromethyl)-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 263157-08-0)
- 5-Bromo-1-ethyl-1H-benzo[d][1,2,3]triazole (CAS 1312139-81-3)
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- 2-(Tetrahydro-2H-thiopyran-4-yl)acetamide (CAS 178243-07-7)
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- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com