(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate CAS 778646-95-0
| CAS No. | 778646-95-0 |
| Molecular Formula | C12H22N2O4 |
| Molecular Weight | 258.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate (CAS 778646-95-0), molecular formula C12H22N2O4 and molecular weight 258.31 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate (C12H22N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 258.31 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2R,4R)-1-tert-Butyl 2-methyl 4-aminopiperidine-1,2-dicarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H22N2O4 |
| Molecular Weight | 258.31 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Recommended Standards
- (2R)-2-amino-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid (CAS 2351455-95-1)
- (2S)-2-amino-2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid (CAS 2351488-61-2)
- (1,2-Dihydroacenaphthylen-5-yl)(phenyl)methanone (CAS 4657-89-0)
- (2S)-2-amino-4-(benzyloxycarbonylamino)butanoic acid (CAS 2130-77-0)
- 3,3-dimethylbutane-1-sulfonyl fluoride (CAS 372-61-2)
- 1-(2-Chloro-4-(4-chlorophenyl)quinolin-3-yl)ethan-1-one (CAS 1376314-02-1)
- tert-butyl (3aS,6aR)-2,2-dioxo-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxathiazole-3-carboxylate (CAS 2145122-45-6)
- Besudil Impurity 1 (CAS CATO-C4X-29881)
- 4-Butyl-3-iodobenzoic acid (CAS 1131588-07-2)
- 2,3-Dihydro-1h-indene-1,2-diamine (CAS 14563-24-7)
- (S)-1-(2-chloro-3-methoxyphenyl)ethan-1-amine (CAS 1212836-37-7)
- 6-Nitroquinoline-2-carbonitrile (CAS 13675-93-9)
- 1-(((4-Bromophenyl)thio)methyl)cyclopentan-1-ol (CAS 1489283-61-5)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
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