Norepinephrine Impurity 81 CAS 779288-87-8
| CAS No. | 779288-87-8 |
| Molecular Formula | C11H17NO3 |
| Molecular Weight | 211.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Norepinephrine Impurity 81 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Norepinephrine Impurity 81 (CAS 779288-87-8), a pharmacopoeial impurity reference standard (molecular formula C11H17NO3, MW 211.26 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Norepinephrine Impurity 81 (C11H17NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H17NO3 |
| Molecular Weight | 211.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 91 (CAS 7760-00-1)
- Norepinephrine Impurity 100 (CAS CATO-C4X-1514100)
- Norepinephrine Impurity 65 (CAS CATO-C4X-151465)
- Norepinephrine Impurity 155 (CAS CATO-C4X-1514155)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 160 (CAS CATO-C4X-1514160)
- Norepinephrine Impurity 23 (CAS 14771-02-9)
- Norepinephrine Impurity 25 (CAS 17345-68-5)
Recommended Standards
- Ondansetron EP Impurity D (CAS 99614-64-9)
- Perindopril EP Impurity L (CAS 111836-22-7)
- Parecoxib sodium Impurity 20 (CAS 952-06-7)
- Oxcarbazepine Impurity 27 (CAS 4014-77-1)
- Valaciclovir Impurity 57 (CAS CATO-C4X-124857)
- Mivacurium chloride Impurity 29 (CAS 53432-90-9)
- Fesoterodine Impurity 16 (CAS 161497-18-3)
- 3-Bromopyrazolo[1,5-a]pyridine-5-carboxylic Acid (CAS 876379-79-2)
- Ramelteon Impurity 5 (CAS 448964-37-2)
- 2-(2-Aminoethyl)isoindoline-1,3-dione (CAS 71824-24-3)
- 3-(Oxetan-3-yloxy)aniline (CAS 1447962-24-4)
- CAS 1512670-99-3 (CAS 1512670-99-3)
- Moexipril Related Compound E (CAS 82586-62-7)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com