2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 779331-12-3
| CAS No. | 779331-12-3 |
| Molecular Formula | C20H22BF3O3 |
| Molecular Weight | 378.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
CATO supplies 2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 779331-12-3), a certified reference material (molecular formula C20H22BF3O3, MW 378.19 g/mol) for analytical method development and quality control.
Owing to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution, 2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-(Benzyloxy)-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22BF3O3 |
| Molecular Weight | 378.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Benzyloxy Standards
- 2-(4-(Benzyloxy)-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1218790-07-8)
- 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1257078-54-8)
- 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 2096995-52-5)
- (R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-bromophenyl)propanoic acid (CAS 123098-44-2)
- 2-(((Benzyloxy)carbonyl)amino)-3-(3-bromophenyl)propanoic acid (CAS 331955-30-7)
- 2-(((Benzyloxy)carbonyl)amino)-3-(4-bromophenyl)propanoic acid (CAS 82611-57-2)
- 3-(((Benzyloxy)carbonyl)amino)-3-(3-bromophenyl)propanoic acid (CAS 778598-15-5)
- 3-(((Benzyloxy)carbonyl)amino)-3-(4-bromophenyl)propanoic acid (CAS 477849-01-7)
Recommended Standards
- 1-((4-Iodo-3-methoxyphenyl)sulfonyl)-4-methyl-1H-imidazole (CAS 898641-07-1)
- (2-(Bis(tert-butoxycarbonyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)boronic acid (CAS 2242682-96-6)
- 4-Iodo-N,N-dimethyl-3-(pyridin-2-yl)-1H-pyrazole-1-sulfonamide (CAS 746668-78-0)
- 4,4,5,5-Tetramethyl-2-(4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-1,3,2-dioxaborolane (CAS 1813554-41-4)
- 2-hydrazinyl-5,6,7,8-tetrahydroquinazolin-4-ol (CAS 118802-45-2)
- N-Desmethyl Nitroso Trimebutine D9 (CAS CATO-C4X-185826)
- 2-(1,3-Dioxo-1,3-dihydro-2H-inden-2-ylidene)malononitrile (CAS 16954-74-8)
- QO-40 (CAS 1259536-70-3)
- 2,3-Diphenylbenzofuran (CAS 13054-95-0)
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