5-Fluoro-2-hydroxybenzeneboronic acid pinacol ester, 97% CAS 779331-49-6
| CAS No. | 779331-49-6 |
| Molecular Formula | C12H16BFO3 |
| Molecular Weight | 238.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Fluoro-2-hydroxybenzeneboronic acid pinacol ester, 97% (C12H16BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Fluoro-2-hydroxybenzeneboronic acid pinacol ester, 97% (CAS 779331-49-6) is a high-purity analytical reference standard with the molecular formula C12H16BFO3 and a molecular weight of 238.06 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16BFO3 |
| Molecular Weight | 238.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-4-hydroxyphenylboronic Acid Pinacol Ester (CAS 1029439-02-8)
- 4-Fluoro-2-hydroxybenzeneboronic acid pinacol ester, 97% (CAS 1038828-32-8)
- 4-Fluoro-3-hydroxybenzeneboronic acid pinacol ester, 97% (CAS 1392234-97-7)
- 4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 1398923-95-9)
- 2-Fluoro-6-hydroxybenzeneboronic acid pinacol ester, 97% (CAS 1534369-41-9)
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- 2-(2-Fluoro-4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 2096997-58-7)
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Recommended Standards
- 5-Bromopyridine-3-sulphonic Acid (CAS 62009-34-1)
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- 5-Chloro-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 102996-32-7)
- 4-azidobutanenitrile (CAS 21994-40-1)
- 6-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)picolinic acid (CAS 1342022-63-2)
- ((3,4-Dimethylphenyl)sulfonyl)glycylglycine (CAS 554426-66-3)
- 1-(5-Hydroxy-2-pyrimidinyl)piperazine 55745-85-2 C8H12N4O W6968 (CAS 55745-85-2)
- 7,9-Dimethyl-2-((4-methylbenzyl)thio)-4-(naphthalen-2-yloxy)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine (CAS 439111-33-8)
- Ethyl 8-methoxy-6-methyl-4-(methylamino)quinoline-3-carboxylate (CAS 1315376-34-1)
- (7-Fluoro-1H-indol-4-yl)boronic acid (CAS 1403348-66-2)
- Dopamine Impurity 19 (CAS 16240-59-8（free base）)
- Methyl 4-formyl-1-methylcyclohexane-1-carboxylate (CAS 1965309-11-8)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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