(R)-2-Hydroxy-2-(4-nitrophenyl)acetic acid CAS 77977-73-2
| CAS No. | 77977-73-2 |
| Molecular Formula | C7F5NS |
| Molecular Weight | 225.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-Hydroxy-2-(4-nitrophenyl)acetic acid.
CATO supplies (R)-2-Hydroxy-2-(4-nitrophenyl)acetic acid (CAS 77977-73-2), a certified reference material (molecular formula C7F5NS, MW 225.14 g/mol) for analytical method development and quality control.
Structurally, (R)-2-Hydroxy-2-(4-nitrophenyl)acetic acid (C7F5NS) contains a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 225.14 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7F5NS |
| Molecular Weight | 225.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4,4,5,5-Tetramethyl-2-(4-(methyl-d3)phenyl-2,3,5,6-d4)-1,3,2-dioxaborolane (CAS 1643415-66-0)
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- 2-Methoxy-6-phenylnicotinonitrile (CAS 85814-99-9)
- 1-{[(4-chlorobenzoyl)oxy]imino}cyclododecane (CAS 252730-97-5)
- 1-Naphthalenecarboxylicacid, 7-methoxy- 7498-58-0 CTK2I1073 (CAS 7498-58-0)
- 4,4,5,5-Tetramethyl-2-(3-vinylphenyl)-1,3,2-dioxaborolane (CAS 627525-99-9)
- 2-(4-Bromothiophen-3-yl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 2096994-66-8)
- (S)-N-(2-(((S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-2-oxoethyl)-1-((S)-2-aminopropanoyl)pyrrolidine-2-carboxamide acetate (CAS 144110-40-7)
- 1-(3,5-Dimethyl-1H-pyrazol-4-yl)-N-methylethan-1-amine oxalate (CAS 1263987-41-2)
- Methyl 2-(2-Bromo-5-methyl-4-thiazolyl)acetate (CAS 496062-15-8)
- Ethyl 3-hydroxyisonicotinate, 97% (CAS 18342-97-7)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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