5-Trimethylsilanyl-thiophene-2-carbonitrile CAS 77998-64-2
| CAS No. | 77998-64-2 |
| Molecular Formula | C8H11NSSi |
| Molecular Weight | 181.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Trimethylsilanyl-thiophene-2-carbonitrile (CAS 77998-64-2), molecular formula C8H11NSSi and molecular weight 181.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Trimethylsilanyl-thiophene-2-carbonitrile (C8H11NSSi) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11NSSi |
| Molecular Weight | 181.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trimethylsilanyl Standards
- 3-Methyl-5-trimethylsilanyl-isoxazole (CAS 54773-26-1)
- 4-Methyl-2-trimethylsilanyl-oxazole (CAS 90892-93-6)
- 5-Trimethylsilanyl-isoxazole-3-carboxylic acid ethyl ester (CAS 149286-32-8)
- 3-(Trimethylsilanyl)propionic Acid 2,5-Dioxopyrrolidin-1-yl Ester (CAS 1445781-54-3)
- 3,5-Bis-trimethylsilanyl-benzoicacid (CAS 125973-55-9)
- 3-(2-Trimethylsilanyl-ethoxymethyl)-6-vinyl-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 1313712-65-0)
Recommended Standards
- 2-(Trimethylsilyl)ethanesulfonamide (CAS 125486-96-6)
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- 1-[2-(trimethylsilyl)ethynyl]piperidine (CAS 115105-41-4)
- 2-(5,6-Dimethoxy-1H-indazol-3-yl)acetic acid (CAS 199533-43-2)
- 1-(2-(tert-Butoxy)-2-oxoethyl)azetidine-3-carboxylic acid (CAS 2200314-40-3)
- 1-Methyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrazole (CAS 1607838-15-2)
- 1-(2-Methoxypyrimidin-5-yl)ethanone (CAS 1056174-56-1)
- 6-BROMO-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE-2-CARBOXYLIC ACID (CAS 1785506-15-1)
- Fmoc-L-Phg(4-Br)-OH (CAS 1260592-26-4)
- 1-(2-Methyl-2H-indazol-6-yl)ethan-1-one (CAS 1159511-29-1)
- 2-((7-Methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl)oxy)acetic acid (CAS 866043-20-1)
- 4-(4-Boc-piperazin-1-yl)benzyl Alcohol (CAS 158985-37-6)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
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