3-Bromothiophene-2-carboxamide CAS 78031-18-2
| CAS No. | 78031-18-2 |
| Molecular Formula | C5H4BrNOS |
| Molecular Weight | 206.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromothiophene-2-carboxamide (C5H4BrNOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-Bromothiophene-2-carboxamide (CAS 78031-18-2), a certified reference material (molecular formula C5H4BrNOS, MW 206.06 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromothiophene-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4BrNOS |
| Molecular Weight | 206.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromothiophene Standards
- (E)-5-bromothiophene-3-carbaldehyde oxime (CAS 18791-96-3)
- 5-Bromothiophene-3-carboxamide (CAS 189329-94-0)
- 2-Bromothiophene-3-carboxamide (CAS 189330-06-1)
- (E)-4-bromothiophene-2-carbaldehyde oxime (CAS 31767-01-8)
- 4-Bromothiophene-2-carboxamide (CAS 83933-17-9)
- 5-Bromothiophene-2-carboxaldehyde oxime (CAS 2160-63-6)
- 4-Bromothiophene-2-carboximidamide (CAS 1094293-83-0)
- 5-Bromothiophene-2-carboximidamide (CAS 844496-26-0)
Recommended Standards
- 2-Bromo-4-methylthiazole-5-carbaldehyde (CAS 933720-87-7)
- 4-Bromo-1H-pyrazole-3-carbothioamide (CAS 289504-61-6)
- 2-Bromo-1-(thiazol-5-yl)ethanone (CAS 201470-17-9)
- 4-Bromo-2-methylthiazole-5-carbaldehyde (CAS 2167792-96-1)
- Rel-(1R,2S)-2-(4-fluorophenyl)cyclopropan-1-amine (CAS 113516-71-5)
- 2-(Difluoromethoxy)pyrazine-6-carboxaldehyde (CAS 1261813-72-2)
- N1,N1-diethyl-N2-methylcyclopentane-1,2-diamine (CAS 1248073-53-1)
- Crisaborole Impurity 39 (CAS 13321-76-1)
- N-1-Adamantylurea (CAS 13072-69-0)
- Imidazo[1,2-a]pyridine-8-carboximidamide (CAS 1541266-80-1)
- 5-(Hydroxymethyl)-3-methyl-1,3-thiazol-2(3H)-one (CAS 2091180-64-0)
- 5-(Tert-butoxy)pentanoic acid (CAS 1039852-53-3)
- 3-Cyclopropoxythiophene-2-carbaldehyde (CAS 2314460-52-9)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com